Adrenomimetic drugs: new aspects

ADRENOMIMETIC DRUGS: NEW DIAGNOSTIC AND THERAPEUTIC ASPECTS IN BRONCHIAL ASTHMA V. N. Solopov, I. V. Lunichkina Summary It is suggested to use alfa-stimulating effect of naphthyzine and halazoline for pharmacological spirometric testing in evaluating the inflammatory-edematous componert of bronchial obstruction. Those antiedemics combined with standard bronchospasmolytics (beta-2-agonists and cholinolytics) proved effective in arresting episodes of …

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Mechanisms of bronchial hyperreactivity

MECHANISMS OF BRONCHIAL HYPERREACTIVITY IN HEALTHY PERSONS V.N.Solopov, S.B.Dogadkina Medical center ‘Pulmonologist’, Moscow, Russia KEY WORDS Bronchial hyperresponsiveness. Microcirculation. Sinus arrhythmia. Nebulized distilled water test. ABSTRACT The interrelation between the bronchial hyperresponsiveness, degree of sinus arrhythmia and the state of the microcirculatory bed was studied in 64 teenagers – 38 males and 26 females aged …

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Oral therapy with expectorants

ORAL THERAPY WITH EXPECTORANTS I. V. Lunichkina, V. N. Solopov Summary Comparative effectiveness of oral expectorants lasolvan, bromhexine and mucodyne has been studied with respect to their effect on the expectoration rate and rheological sputum properties, adhesiveness and viscid-elasticity. Lasolvan and Bromhexine have effect predominantly on sputum adhesion whereas mucodyne on viscid-elastic properties. The expedience …

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Non-conventional approaches to sputum investigations in patients with COPD

V. N. Solopov, I. I. Reznikov, I. V. Lunichkina Non-conventional approaches to sputum investigations in patients with COPD Soviet Association of aid to patients with cystic fibrosis, Pogodinscaya 8 – 2, 119121 Moscow, USSR. We applied the method of electron paramagnetic resonance (EPR) radiospectroscopy to the determination of free sulphydryl groups (SH groups) concentration in …

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Expectoration disturbances in patients with COPD

V. N. Solopov, I. V. Lunichkina Expectoration disturbances in patients with COPD Soviet Association of aid to patients with cystic fibrosis Pogodinscaya 8 – 2, 119121 Moscow, USSR. We developed a method of estimation of the evacuation time (expectoration time) (Texp) of bronchial contents stained with haemoglobin (Hb) in patients with COPD. 155 patients were …

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Diagnostic program for investigating mucociliar transport in patients with chronic nonspecific diseases of the lungs

A. G. Chuchalin, V. N. Solopov, N. A. Kolganova DIAGNOSTIC PROGRAM FOR INVESTIGATING MUCOCILIAR TRANSPORT IN PATIENTS WITH CHRONIC NONSPECIFIC DISEASES OF THE LUNGS Indices of mucociliar transport: its rate and sputum reological properties were studied. Data indicative of close relation between mucociliar transport disorders and obstructive syndrome are presented. Possible mechanisms of bronchial patency …

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The diagnosis of mucociliary insufficiency

THE DIAGNOSIS OF MUCOCILIARY INSUFFICIENCY V. N. Solopov, I. V. Lunichkina Summary The data on the diagnosis of mucociliary insufficiency (MCI) are reviewed for patients with chronic obstructive pulmonary diseases. MCI is characterized as the condition of more rapid accumulation of bronchial secretion in comparison to its evacuation, the residual secretion being the cause of …

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Endobronchial therapy in chronic bronchitis patients

ENDOBRONCHIAL THERAPY IN CHRONIC BRONCHITIS PATIENTS V. N. Solopov, I. V. Lunichkina Summary The paper is devoted to questions related to the endobronchial administration of medicamentous agents — antibacterial preparations, expectorants, etc. in the treatment of chronic bronchitis. A modified turbo-inhaler «Spinhaler» is used for the endobronchial introduction of an expectorant—sodium bicarbonate in a powder …

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