Mucociliary Function in Chronic Bronchitis

MUCOCILIARY FUNCTION IN CHRONIC BRONCHITIS V. N. Solopov, I. V. Lunichkina Summary A study of mucociliary transport in patients with chronic bronchitis (nonobstructive, obstructive, purulent and pyo-obstructive forms) has demonstrated that the mucociliary transport rate differs significantly between different groups of patients. The pattern of bronchial excretion of the indicator substance (patients endogenic hemoglobin), inhaled …

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Treatment of chronic bronchitis by endobronchial administration of antibiotics

TREATMENT OF CHRONIC BRONCHITIS BY ENDOBRONCHIAL ADMINISTRATION OF ANTIBIOTICS A procedure for administration of antibacterial drugs with a turboinhaler of the spinhaler type is described. Antibiotics of various groups were used for endobronchial administration: penicillins, cephalosporins, aminoglycosides and nitrofuran derivatives. The data on high efficacy of the procedure in treatment of patients with chronic recurring …

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A man who can cure asthma

«Moscow news», No. 17, April 29-May 5, 1994 A man who can cure asthma An unknown Russian scientist has solved a world riddle but is not in a position to give vent to his ideas SOLUTION IS NEAR? In 1975 Victor Solopov, a military engineer-chemist, was discharged from the USSR Armed Forces. A year later …

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Adrenomimetic drugs: new aspects

ADRENOMIMETIC DRUGS: NEW DIAGNOSTIC AND THERAPEUTIC ASPECTS IN BRONCHIAL ASTHMA V. N. Solopov, I. V. Lunichkina Summary It is suggested to use alfa-stimulating effect of naphthyzine and halazoline for pharmacological spirometric testing in evaluating the inflammatory-edematous componert of bronchial obstruction. Those antiedemics combined with standard bronchospasmolytics (beta-2-agonists and cholinolytics) proved effective in arresting episodes of …

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Mechanisms of bronchial hyperreactivity

MECHANISMS OF BRONCHIAL HYPERREACTIVITY IN HEALTHY PERSONS V.N.Solopov, S.B.Dogadkina Medical center ‘Pulmonologist’, Moscow, Russia KEY WORDS Bronchial hyperresponsiveness. Microcirculation. Sinus arrhythmia. Nebulized distilled water test. ABSTRACT The interrelation between the bronchial hyperresponsiveness, degree of sinus arrhythmia and the state of the microcirculatory bed was studied in 64 teenagers – 38 males and 26 females aged …

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Oral therapy with expectorants

ORAL THERAPY WITH EXPECTORANTS I. V. Lunichkina, V. N. Solopov Summary Comparative effectiveness of oral expectorants lasolvan, bromhexine and mucodyne has been studied with respect to their effect on the expectoration rate and rheological sputum properties, adhesiveness and viscid-elasticity. Lasolvan and Bromhexine have effect predominantly on sputum adhesion whereas mucodyne on viscid-elastic properties. The expedience …

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Evolution in asthma — evolution of bronchial response to epinephrine

EVOLUTION IN ASTHMA — EVOLUTION OF BRONCHIAL RESPONSE TO EPINEPHRINE Dr. Victor N. Solopov «Asthma Service», Medical Services Ltd., Moscow KEY WORDS Asthma evolution. Fenoterol. Epinephrine. Sudden death from asthma ABSTRACT The different types of bronchial response to fenoterol (Fen) and epinephrine (Epi) resulted after their consecutive inhalation and interaction in patients’ airways depending on …

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All the beta-2 bronchodilators are able to provoke sudden death in asthmatics

ALL THE BETA-2 BRONCHODILATORS ARE ABLE TO PROVOKE SUDDEN DEATH IN ASTHMATICS Dr. Victor N. Solopov «Asthma Service», Medical Services Ltd., Moscow KEY WORDS Albuterol. Fenoterol. Formoterol. Epinephrine. Sudden death from asthma ABSTRACT The different types of bronchial response to Albuterol (Alb), Fenoterol (Fen), Formoterol (Frm) and epinephrine (Epi) resulted after their consecutive inhalation and …

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Non-conventional approaches to sputum investigations in patients with COPD

V. N. Solopov, I. I. Reznikov, I. V. Lunichkina Non-conventional approaches to sputum investigations in patients with COPD Soviet Association of aid to patients with cystic fibrosis, Pogodinscaya 8 – 2, 119121 Moscow, USSR. We applied the method of electron paramagnetic resonance (EPR) radiospectroscopy to the determination of free sulphydryl groups (SH groups) concentration in …

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Expectoration disturbances in patients with COPD

V. N. Solopov, I. V. Lunichkina Expectoration disturbances in patients with COPD Soviet Association of aid to patients with cystic fibrosis Pogodinscaya 8 – 2, 119121 Moscow, USSR. We developed a method of estimation of the evacuation time (expectoration time) (Texp) of bronchial contents stained with haemoglobin (Hb) in patients with COPD. 155 patients were …

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Diagnostic program for investigating mucociliar transport in patients with chronic nonspecific diseases of the lungs

A. G. Chuchalin, V. N. Solopov, N. A. Kolganova DIAGNOSTIC PROGRAM FOR INVESTIGATING MUCOCILIAR TRANSPORT IN PATIENTS WITH CHRONIC NONSPECIFIC DISEASES OF THE LUNGS Indices of mucociliar transport: its rate and sputum reological properties were studied. Data indicative of close relation between mucociliar transport disorders and obstructive syndrome are presented. Possible mechanisms of bronchial patency …

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The diagnosis of mucociliary insufficiency

THE DIAGNOSIS OF MUCOCILIARY INSUFFICIENCY V. N. Solopov, I. V. Lunichkina Summary The data on the diagnosis of mucociliary insufficiency (MCI) are reviewed for patients with chronic obstructive pulmonary diseases. MCI is characterized as the condition of more rapid accumulation of bronchial secretion in comparison to its evacuation, the residual secretion being the cause of …

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